Polyneuropathy Due to Cyclosporine A in Patients with Renal Transplantation: A Case Report

Sayin R., Soyoral Y. U. , Erkoc R.

RENAL FAILURE, cilt.33, sa.5, ss.528-530, 2011 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Konu: 5
  • Basım Tarihi: 2011
  • Doi Numarası: 10.3109/0886022x.2011.573893
  • Dergi Adı: RENAL FAILURE
  • Sayfa Sayıları: ss.528-530


Background: Calcineurin inhibitor cyclosporine A (CsA) is a potent immunosuppressive agent. The side effects of CsA include nephrotoxicity, hypertension, hypertrichosis, infection, hyperpotassemia, and, to a lower extent, neuropathy. Objectives: In this case report, we aimed to present a renal transplant patient with polyneuropathy (PNP) due to the use of CsA and with improvement when switched to rapamycin. Methods: In electromyography, axonal sensory PNP was detected. CsA was stopped and rapamycin was begun. Results: His complaints rapidly improved after using rapamycin. Conclusions: Patients using CsA should be closely monitored for peripheral neuropathy and in case of toxicity, alternative immunosuppressive agents should be considered.