Akademik Veri Yönetim Sistemi
6th INTERNATIONAL CONFERENCE ON GLOBAL PRACTICE OF MULTIDISCIPLINARY SCIENTIFIC STUDIES, Lisbon, Portekiz, 9 - 16 Nisan 2024, ss.625-630
Positron emission tomography (PET) is a molecular imaging method used in the diagnosis, staging, evaluation of response to treatment, radiotherapy planning and prognosis determination of various malignancies. Its working principle is based on the formation of gamma anhylation photons with an energy of 511 keV. Before the PET scan, radiopharmaceuticals, which are a source of β+ (positron) rays, are given to the body. Radioactive elements 18F (Fluorine) and 68Ga (Gallium) are commonly used. 18F, which is most commonly used in PET/CT imaging of oncological studies, has a half-life of 109.8 minutes. Glucose metabolism appears to be increased in tumor cells compared to healthy cells. The tumor imaging technique of (18F) labeled Fluorodeoxyglucose (FDG) is based on this. Thus, using (18F)-FDG, most malignant tumors can be imaged noninvasively by increasing glucose metabolism. The structural formula of (18F)-FDG is written as C6H11O5F18. Maximum effective dose equivalent: 0.11 rem/mCi (0.019 mSv/MBq).In this research, ionizing electromagnetic radiation (EMR) interaction parameters namely mass attenuation coeffıcients (μρ), effective atomic number (Zeff) and electron densities (Nel) of C6H11FO5 compound have been computed in the energy range 1 keV–100 GeV. EMR interaction parameters evaluated in the this work could be beneficial in radiation dosimetry and therapy.
Keywords: Effective atomic number, Electron densities, Fluorodeoxyglucose, Mass attenuation coefficients