Low levels of circulating platelet factor 4 (PF4, CXCL4) in subclinically hypothyroid autoimmune thyroiditis


GORAR S., ADEMOGLU E., Carlioglu A., ALIOGLU B., BEKDEMIR H., SAGLAM B., ...More

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, vol.39, no.2, pp.185-189, 2016 (SCI-Expanded) identifier identifier identifier

Abstract

Purpose Chemokines play an important role in the pathogenesis of autoimmune thyroid diseases. Platelet factor 4 (PF4, CXCL4) released from activated platelets is a chemokine. However, its clinical importance in autoimmune thyroiditis remains unknown. This study is intended to determine circulating levels of PF4 levels in patients with autoimmune thyroiditis (AIT).