Accelerated atherosclerosis in haemodialysis patients; correlation of endothelial function with oxidative DNA damage

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KAYA Y., ARI E., Demir H., SOYLEMEZ N., Cebi A., Alp H., ...More

NEPHROLOGY DIALYSIS TRANSPLANTATION, vol.27, no.3, pp.1164-1169, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.1093/ndt/gfr443
  • Journal Name: NEPHROLOGY DIALYSIS TRANSPLANTATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1164-1169
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

Background. Accelerated atherosclerosis is the major cause of mortality in patients on chronic haemodialysis (HD). The aim of this study was to evaluate the relationship between oxidative DNA damage [8-hydroxy-2'-deoxyguanosine/deoxyguanosine ratio (8-OHdG/dG ratio)], oxidative stress biomarkers and endothelial function in HD patients as an indicator of atherosclerosis.