Accelerated atherosclerosis in haemodialysis patients; correlation of endothelial function with oxidative DNA damage

KAYA, Yüksel; ARI, Elif; Demir, Halit; SOYLEMEZ, Nihat; Cebi, Aysegul; Alp, Hamit; BAKAN, Ebubekir; Gecit, İlhan; AŞICIOĞLU, EBRU; BEYTUR, ALİ

doi:10.1093/ndt/gfr443

Accelerated atherosclerosis in haemodialysis patients; correlation of endothelial function with oxidative DNA damage

KAYA Y., ARI E., Demir H., SOYLEMEZ N., Cebi A., Alp H. H., ...Daha Fazla

NEPHROLOGY DIALYSIS TRANSPLANTATION, cilt.27, sa.3, ss.1164-1169, 2012 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 27 Sayı: 3
Basım Tarihi: 2012
Doi Numarası: 10.1093/ndt/gfr443
Dergi Adı: NEPHROLOGY DIALYSIS TRANSPLANTATION
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1164-1169
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Background. Accelerated atherosclerosis is the major cause of mortality in patients on chronic haemodialysis (HD). The aim of this study was to evaluate the relationship between oxidative DNA damage [8-hydroxy-2'-deoxyguanosine/deoxyguanosine ratio (8-OHdG/dG ratio)], oxidative stress biomarkers and endothelial function in HD patients as an indicator of atherosclerosis.