Accelerated atherosclerosis in haemodialysis patients; correlation of endothelial function with oxidative DNA damage


Creative Commons License

KAYA Y. , ARI E., Demir H. , SOYLEMEZ N., Cebi A., Alp H., ...More

NEPHROLOGY DIALYSIS TRANSPLANTATION, vol.27, no.3, pp.1164-1169, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.1093/ndt/gfr443
  • Title of Journal : NEPHROLOGY DIALYSIS TRANSPLANTATION
  • Page Numbers: pp.1164-1169

Abstract

Background. Accelerated atherosclerosis is the major cause of mortality in patients on chronic haemodialysis (HD). The aim of this study was to evaluate the relationship between oxidative DNA damage [8-hydroxy-2'-deoxyguanosine/deoxyguanosine ratio (8-OHdG/dG ratio)], oxidative stress biomarkers and endothelial function in HD patients as an indicator of atherosclerosis.