Accelerated atherosclerosis in haemodialysis patients; correlation of endothelial function with oxidative DNA damage

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KAYA Y. , ARI E., Demir H. , SOYLEMEZ N., Cebi A., Alp H., et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION, cilt.27, ss.1164-1169, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 27 Konu: 3
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1093/ndt/gfr443
  • Dergi Adı: NEPHROLOGY DIALYSIS TRANSPLANTATION
  • Sayfa Sayısı: ss.1164-1169

Özet

Background. Accelerated atherosclerosis is the major cause of mortality in patients on chronic haemodialysis (HD). The aim of this study was to evaluate the relationship between oxidative DNA damage [8-hydroxy-2'-deoxyguanosine/deoxyguanosine ratio (8-OHdG/dG ratio)], oxidative stress biomarkers and endothelial function in HD patients as an indicator of atherosclerosis.