An investigation of 8-hydroxy-2 '-deoxyguanosine and 8-iso-prostaglandin F-2 alpha levels in patients with larynx carcinoma

Çetin Y. S., Duzenli U., Berköz M., Özkan H., Bozan N.

ENT UPDATES, cilt.10, sa.2, ss.335-339, 2020 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Sayı: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.32448/entupdates.744725
  • Dergi Adı: ENT UPDATES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.335-339
  • Anahtar Kelimeler: Larynx cancer, oxidative stress, 8-hydroxy-2&amp, prostaglandin F2 alpha, PRIME, -deoxyguanosine, OXIDATIVE DNA-DAMAGE, STRESS, HEAD, BIOMARKERS, INCREASE, SMOKING
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Objective: 8-hydroxy-2'-deoxyguanosine (8-OHdG) and 8-iso-prostaglandin F-2(alpha) (8-iso-PGF(2)(alpha)) are indicators of oxidative stress in the human body. The aim of the present study was to investigate serum 8-OHdG and 8-iso-PGF(2)(alpha) levels in patients with larynx carcinoma and to compare them with healthy controls.