An investigation of 8-hydroxy-2 '-deoxyguanosine and 8-iso-prostaglandin F-2 alpha levels in patients with larynx carcinoma


Çetin Y. S. , Duzenli U. , Berköz M. , Özkan H. , Bozan N.

ENT UPDATES, vol.10, no.2, pp.335-339, 2020 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 2
  • Publication Date: 2020
  • Doi Number: 10.32448/entupdates.744725
  • Title of Journal : ENT UPDATES
  • Page Numbers: pp.335-339
  • Keywords: Larynx cancer, oxidative stress, 8-hydroxy-2&amp, prostaglandin F2 alpha, PRIME, -deoxyguanosine, OXIDATIVE DNA-DAMAGE, STRESS, HEAD, BIOMARKERS, INCREASE, SMOKING

Abstract

Objective: 8-hydroxy-2'-deoxyguanosine (8-OHdG) and 8-iso-prostaglandin F-2(alpha) (8-iso-PGF(2)(alpha)) are indicators of oxidative stress in the human body. The aim of the present study was to investigate serum 8-OHdG and 8-iso-PGF(2)(alpha) levels in patients with larynx carcinoma and to compare them with healthy controls.