Identification of 3-Bromo-1-Ethyl-1H-Indole as a Potent Anticancer Agent with Promising Inhibitory Effects on GST Isozymes

Yılmaz, Can; Arslan, Sevki; Mutlu, Dogukan; Konuş, Metin; Kayhan, Abdussamet; Kurt-Kizildogan, Aslihan; Otur, Cigdem; Ozok, Omriye; Kivrak, Arif

doi:10.2174/1871520620666200918111940

Identification of 3-Bromo-1-Ethyl-1H-Indole as a Potent Anticancer Agent with Promising Inhibitory Effects on GST Isozymes

Yılmaz C., Arslan S., Mutlu D., Konuş M., Kayhan A., Kurt-Kizildogan A., ...Daha Fazla

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, cilt.21, sa.6, ss.1292-1300, 2021 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 21 Sayı: 6
Basım Tarihi: 2021
Doi Numarası: 10.2174/1871520620666200918111940
Dergi Adı: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
Sayfa Sayıları: ss.1292-1300
Anahtar Kelimeler: Indole, biological activities, cytotoxicity, antioxidant activity, antimicrobial activity, anti-cancer, GLUTATHIONE-S-TRANSFERASE, INDOLE-DERIVATIVES, BIOLOGICAL-ACTIVITIES, ANTIOXIDANT ACTIVITY, ANTITUMOR-ACTIVITY, NATURAL-PRODUCTS, CANCER, FOODS, PI
Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Background: Indole-based heterocyclic compounds play important roles in pharmaceutical chemistry due to their unexpected biological and pharmacological properties.