Preparation of molecularly imprinted PDMS elastomer for selective detection of folic acid in orange juice
APPLIED SURFACE SCIENCE, cilt.471, ss.168-175, 2019 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 471
- Basım Tarihi: 2019
- Doi Numarası: 10.1016/j.apsusc.2018.12.008
- Dergi Adı: APPLIED SURFACE SCIENCE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.168-175
- Anahtar Kelimeler: Molecularly imprinted polymers, Poly(dimethylsiloxane) elastomer, Folic acid, Surface initiated RAFT polymerization, SOLID-PHASE EXTRACTION, PASTE ELECTRODE, VOLTAMMETRIC DETERMINATION, SURFACE MODIFICATION, POLYMERS, NANOPARTICLES, RECOGNITION, PERFORMANCE, ADSORPTION, POLYMERIZATION
- Van Yüzüncü Yıl Üniversitesi Adresli: Evet
Özet
Herein, it is reported an effective method to prepare novel molecularly imprinted polymers (MIP) on poly(dimethylsiloxane) (PDMS) elastomer via a combination of non-covalent imprinting approach and surface initiated reversible addition fragmentation chain transfer (SI-RAFT) polymerization for sensitive and selective detection of folic acid (FA). For this purpose, 2-(2-Methoxyethoxy) ethyl methacrylate (MEOMA), ethylene glycol dimethacrylate (EGDMA), azobisisobutyronitrile (AIBN), FA and dimethylsulfoxide (DMSO) were used as functional monomer, cross-linker, initiator, template molecule, and porogen, respectively. The adsorption behavior followed the Scatchard equation between FA and PDMS-MIP with a saturation adsorption capacity of 4.51 mg/g and pseudo-second-order kinetics with 60 min equilibrium adsorption time. Furthermore, PDMS-MIP elastomer was successfully applied for selective extraction and detection of FA from orange juice with sufficient recovery (95.5-100.5%) and relative standard deviation less than 7.0%. The limit of detection (LOD) for FA was found to be 0.0031 mu g/mL with a linear range between 0.01 and 100 mu g/mL and a correlation coefficient of 0.9997. Results showed the proposed method could easily, efficiently and selectively extracted FA from complex media. Note that this novel proposed method will open a new way to detect any selected molecules such as pesticide, protein, drug, etc. using molecularly imprinted PDMS elastomer materials.