Evaluation of the retinal nerve fiber layer with optic coherence tomography in patients with alcohol use disorder Évaluation de la couche de fibres nerveuses rétiniennes par tomographie cohérence optique parmi les patients souffrant des désordres liés à la consommation d'alcool

Şahin T., Karadere M., Yıldız V., Çobanoğlu E.

Journal Francais d'Ophtalmologie, cilt.44, sa.5, ss.665-669, 2021 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 5
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.jfo.2020.11.009
  • Dergi Adı: Journal Francais d'Ophtalmologie
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.665-669
  • Anahtar Kelimeler: Alcohol and tobacco use disorder, Optical coherence tomography, Retinal nerve fiber layer thinning, Spectral-domain, Toxic optic neuropathy
  • Van Yüzüncü Yıl Üniversitesi Adresli: Hayır

Özet

Objective: This study aims to evaluate the retinal nerve fiber layer (RNFL) with optical coherence tomography (OCT) among patients with alcohol and tobacco use disorder. Methods: This study included 29 patients and 29 age and gender-matched healthy participants without alcohol dependency. The patients underwent full ophthalmologic examination including visual acuity, intraocular pressure, anterior segment and fundus examinations, and RNFL measurements taken with spectral-domain OCT. The RNFL values of the two groups were compared with each other. Results: In comparison to the control group, the RNFL was found to be thinner in all quadrants in the group with alcohol and tobacco dependency. The RNFL thinning in the superotemporal, temporal, and inferotemporal quadrants was found to be statistically significant (P-values 0.012, 0.040 and 0.005, respectively). Conclusions: Chronic alcohol and tobacco use may cause RNFL thinning. Assessment of RNFL thinning by OCT among patients with alcohol and tobacco dependency might be used to identify visual morbidity.