Doppler analysis of uterine perfusion and ovarian stromal blood flow in polycystic ovary syndrome


Adalı E., Kolusarı A. , ADALI F., Yildizhan R. , Kurdoğlu M., Şahin H. G.

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, cilt.105, ss.154-157, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 105 Konu: 2
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.ijgo.2008.12.023
  • Dergi Adı: INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
  • Sayfa Sayıları: ss.154-157

Özet

Objective: To investigate blood flow velocity in the ovarian stromal artery and uterine artery in women with polycystic ovary syndrome (PCOS) and to correlate these velocities with clinical and biochemical parameters. Methods: A prospective study was carried out in 55 patients with PCOS and 42 age-matched women who did not have PCOS. Clinical, biochemical, and hormonal characteristics, and utero-ovarian Doppler ultrasound blood flow parameters were determined, and correlations between the parameters were evaluated. Results: Ovarian stromal blood flow was higher (P<0.01) and uterine perfusion was lower (P<0.01) in women with PCOS compared with women who did not have PCOS. Ovarian stromal artery pulsatility index (PI) was inversely correlated with levels of dehydroepiandrosterone sulfate (DHEAS) and insulin-like growth factor-1, and with the luteinizing hormone/follicle-stimulating hormone ratio. There was a positive correlation between uterine artery PI and DHEAS level. Conclusion: Doppler analysis of the uterine and intraovarian arteries may provide additional information about the etiopathogenesis of PCOS and partly explain the clinical implications of the condition. (C) 2009 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.