Design, Synthesis, and In vitro Evaluation of Thieno[a]dibenzothiophene Derivatives


Konuş M. , Algso M. A. S. , Kavak E., KURT KIZILDOĞAN A., Yılmaz C. , Kıvrak A.

CHEMISTRYSELECT, cilt.5, ss.3700-3709, 2020 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 5 Konu: 12
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1002/slct.202000685
  • Dergi Adı: CHEMISTRYSELECT
  • Sayfa Sayıları: ss.3700-3709

Özet

A variety of highly substituted thieno[2,3-a]dibenzothiophenes and thieno[3,2-a]dibenzothiophenes are readily prepared via cascade electrophilic cyclization reaction. The reaction was tolerated a variety of compounds. In the present study, antimicrobial and antifungal activities were investigated for all synthesized molecules against A. niger ATCC 16404, C. albicans ATCC 10231, S. aureus ATCC 25923 and B. subtilis ATCC 6633, respectively.