The antioxidant activity and phenolic compounds content of pomace from the berries of ‘Isabella’ and ‘Katıkara’ grape varieties widely produced in the Eastern Black Sea region of Turkey were researched for use as a potential natural
antioxidant source. The results of this study indicated that there were statistically significant differences (p< 0.05) between two varieties for some biochemical compounds. There are high positive correlations among antioxidant activity, phenolic
compounds and ‘Isabella’. Similarly, catechin, citric acid, epicatechin, tartaric acid, total phenolic, vitamin C, gallic acid and p-coumaric acid are strongly and positively correlated with each other. It was observed that ‘Isabella’ grapes presented
higher antioxidant potential with relating presence of high content of phenolic compounds. Mineral elements, which are of great importance for cell protection and healthy teeth, bone and skin structure, were found widely in the ‘Katıkara’
variety. As a result, we can concluded that consuming these two grape varieties will provide significant benefits in blood pressure, heart rhythm, muscle functions, protection of fluid balance in the body, reproduction and many other functions
in the human body.