Analysis of The Clinical and Demographic Data of The Patients Diagnosed With Myastenia Gravis Followed-Up In Our Clinic


Yılgör A., Baydar C.

Eastern Journal of Medicine, vol.28, no.4, pp.778-782, 2023 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 4
  • Publication Date: 2023
  • Doi Number: 10.5505/ejm.2023.15707
  • Journal Name: Eastern Journal of Medicine
  • Journal Indexes: Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.778-782
  • Keywords: Acetylcholine Receptor, Myastenia Gravis, Thymoma
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

Objective: The objective of this study is to evaluate the demographic characteristics as well as the clinical course, antibod y, and electrophysiological characteristics of the patients diagnosed with Myastenia Gravis (MG ) followed-up in our clinic. Material and Method: The demographic characteristics as well as the radiological characteristics, clinical follow-ups, antibody results and electrophysiological characteristics of 99 MG patients followed-up in our Neuromuscular and Muscle Diseases Outpatient Clinic for a period of 5 years are examined. Findings: The mean age of the patients was 44,38±15,2. The number of patients followed-up as isolated ocular MG was 22,22% (n=22). Acetylcholine receptor antibody (AntiAChRAb) was found positive in 53,54% (n=53) of the patients and thymus pathology (Thymoma + post-thymectomy thymic hyperplasia) was found in the thoracic tomography of 42,42% (n=42) of the patients. Result: Although the pathologies in the development of MG are well known, in some cases, there may be some problems in the follow-up and treatment of MG patients. Therefore, detailed patient follow-up and long-term clinical monitoring is important in MG patients. There are some limitations due to the fact that this is a h ospital-based study. An example of such limitations is the lack of data related to responses to the treatment. More extensive epidemiological studies on this matter will be more informative. Detailed patient file recording and administration of individuali zed treatments will provide positive results in the long term in MG patients who suffer from a chronic disease which progress with flare ups.