Astragalus guzelsuensis F. Ghahrem.-Nejad, Behcet & Demir sp. nova (Fabaceae), endemic to the eastern Anatolia, Turkey, is described here. It is placed in the sect. Incani due to its medifixed hairs, free stipules, bibracteolate flowers, and imparipinnate leaves, and it appears to be most closely related to A. siahcheshmehensis. Astragalus guzelsuensis differs, among other things, in having more leaflets (6-10 not 2-6 pairs), longer stipules (8-13 mm not 3-4 mm), a glabrous calyx (not hairy), a longer standard (29-31 not 25 mm), and a glabrous fruit (not hairy).