In this work, novel superporous composite cryogel using natural source such as carboxymethyl cellulose (CMC) and halloysite nanotubes (Hal nanotubes) was prepared. The composite was prepared via cryogelation method including the Hal nanotubes within polymeric matrices before cryogelation. A series of the Hal nanotubes/carboxymethyl cellulose composite were prepared by varying the used amounts of crosslinker, and Hal nano tubes amounts. Additionally, Hal nanotubes were modified with different modifying agent such as (3-aminopropyl)triethoxysilane (APTES), (3-chloro-2-hydroxypropyl)trimethylammonium chloride (CHPTACI), polyethylenimine (PEI), epichlorohydrin (ECH), diethylenetriamine (DETA), taurine (TA), and tris(2-aminoethyl)amine (TAEA), these modified Hal nanotubes were used in CMC cryogel composite preparation. Characterization of the synthesized materials was performed by Scanning and Transmission Electron Microscopy (SEM and TEM), Zeta Potential (ZP) measurement, Thermogravimetric Analysis (TGA), Fourier Transform Infrared (FT-IR) spectroscopic measurement and Surface area and Porosity Analyzer. (C) 2017 Elsevier B.V. All rights reserved.