ıV-International Congress of Food, Agriculture and Veterinary Sciences, Van, Türkiye, 27 - 28 Mayıs 2022, cilt.1, sa.1, ss.38
Sequence-based
approaches precisely determine the nucleic acid sequence of a particular DNA or
cDNA (RNA) molecule. Next-generation sequencing (NGS) or high-throughput
sequencing not only saves time but also enables orders of magnitude more data
to be delivered at a much lower cost. Depending on their development and
implementation time, NGS platforms can be divided into first, second, and third-generation sequencing technologies, also known as de novo genome assembly. In
addition to 3rd NGS, 4th and even 5th NGS technologies and methods were also
mentioned, as well as their use and application in all living organisms
(bacteria, plants, humans) of genomic research in the near future.
In this
study, the NGS-related platforms and their bioinformatics or computational
analysis previously applied to farm animal genomes were used to provide a brief
overview of the advances, applications, and challenges of NGS platforms.