Neuroprotective effects of erythropoietin against oxidant injury following brain irradiation: an experimental study
ARCHIVES OF MEDICAL SCIENCE, cilt.12, sa.6, ss.1348-1353, 2016 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 12 Sayı: 6
- Basım Tarihi: 2016
- Doi Numarası: 10.5114/aoms.2016.58622
- Dergi Adı: ARCHIVES OF MEDICAL SCIENCE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1348-1353
- Anahtar Kelimeler: brain, irradiation, oxidant injury, neuroprotective effects, erythropoietin, CENTRAL-NERVOUS-SYSTEM, RECOMBINANT-HUMAN-ERYTHROPOIETIN, RADIATION-INDUCED APOPTOSIS, OXIDATIVE-STRESS, RAT, MECHANISMS, PROTECTION, TOXICITY, RADICALS
- Van Yüzüncü Yıl Üniversitesi Adresli: Evet
Özet
Introduction: Radiation therapy (RT) is a major treatment modality, and the central nervous system is a dose-limiting organ in clinical RT. This experimental study aims to present the evaluation of the neuroprotective effects of erythropoietin (EPO) against oxidant injury following brain irradiation in rats.