Voltammetric Investigation of Antiviral Drug Valacyclovir at a Boron-Doped Diamond Electrode in Different Electrolyte Media: Its Determination Enhanced by Anionic Surfactant in Pharmaceuticals and Biological Fluids

Talay Pınar, Pınar; Şentürk, Zühre

doi:10.2174/1573412912666160901102844

Voltammetric Investigation of Antiviral Drug Valacyclovir at a Boron-Doped Diamond Electrode in Different Electrolyte Media: Its Determination Enhanced by Anionic Surfactant in Pharmaceuticals and Biological Fluids

Atıf İçin Kopyala

Talay Pınar P. , Şentürk Z.

CURRENT PHARMACEUTICAL ANALYSIS, cilt.13, ss.175-187, 2017 (SCI İndekslerine Giren Dergi)

Cilt numarası: 13 Konu: 2
Basım Tarihi: 2017
Doi Numarası: 10.2174/1573412912666160901102844
Dergi Adı: CURRENT PHARMACEUTICAL ANALYSIS
Sayfa Sayıları: ss.175-187

Özet

Background: The electrochemical oxidation of antiviral drug valacyclovir was first investigated in aqueous and aqueous/surfactant solutions by cyclic and linear sweep voltammetry using a borondoped diamond electrode. The compound was oxidized in one, two or three steps at high positive potentials, depending on pH and composition of the supporting electrolyte, scan rate and surfactant type.