Voltammetric Investigation of Antiviral Drug Valacyclovir at a Boron-Doped Diamond Electrode in Different Electrolyte Media: Its Determination Enhanced by Anionic Surfactant in Pharmaceuticals and Biological Fluids

Talay Pınar, Pınar; Şentürk, Zühre

doi:10.2174/1573412912666160901102844

Voltammetric Investigation of Antiviral Drug Valacyclovir at a Boron-Doped Diamond Electrode in Different Electrolyte Media: Its Determination Enhanced by Anionic Surfactant in Pharmaceuticals and Biological Fluids

Talay Pınar P. , Şentürk Z.

CURRENT PHARMACEUTICAL ANALYSIS, vol.13, no.2, pp.175-187, 2017 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 13 Issue: 2
Publication Date: 2017
Doi Number: 10.2174/1573412912666160901102844
Title of Journal : CURRENT PHARMACEUTICAL ANALYSIS
Page Numbers: pp.175-187

Abstract

Background: The electrochemical oxidation of antiviral drug valacyclovir was first investigated in aqueous and aqueous/surfactant solutions by cyclic and linear sweep voltammetry using a borondoped diamond electrode. The compound was oxidized in one, two or three steps at high positive potentials, depending on pH and composition of the supporting electrolyte, scan rate and surfactant type.