The Effect of Long-Term Exercise Training with Omega3 Fatty Acid Supplement on Serum Iris and Some Blood Parameters

Aslan M., Sarikaya M.

MEDICAL SCIENCE, vol.26, pp.1-11, 2022 (ESCI)

  • Publication Type: Article / Article
  • Volume: 26
  • Publication Date: 2022
  • Journal Name: MEDICAL SCIENCE
  • Journal Indexes: Emerging Sources Citation Index (ESCI)
  • Page Numbers: pp.1-11
  • Van Yüzüncü Yıl University Affiliated: Yes


This research; the effects of omega-3 fatty acids and exercise on irisin, leptin and ghrelin hormone total cholesterol, HDL, LDL and triglyceride levels when applied separately or in combination were investigated. Method; A total of 28 male Wistar albino rats, 8 weeks old, were randomly divided into 4 groups of seven each as control, exercise, omega (400 mg/kg) and exercise + omega-3. After starting the omega-3 fatty acid diet, rats were subjected to a 20-minute jog test 5 days a week for 10 weeks. Results; It was determined that exercise and omega-3 supplementation decreased the total cholesterol level in the groups in which they were applied separately, and increased the total cholesterol level when they were applied together. When we examined the triglyceride levels, it was determined that while there was an increase in the exercise group, there was a decrease in the omega group, and when the exercise and omega-3 supplementation were combined, it decreased similarly to the omega group. In addition, when we examined HDL and LDL cholesterol levels, it was found that exercise and omega-3 fatty acids increased HDL levels separately and in combination, LDL levels decreased in omega-3 and exercise groups, but there was no change in cholesterol levels. Conclusion; positive effects of exercise on lipid profile and iris, moderate positive correlation between irisin and leptin; It can be said that irisin and ghrelin show a highly positive relationship and omega-3 fatty acids have positive effects on the lipid profile.