INVESTIGATION OF PHOTON DOSES REACH ING HEALTHYTISSUES IN THE USE OF DIFFERENT NEUTRON ENERGIES INBORON NEUTRON CAPTURE THERAPY


Tuğrul T.

Nuclear Technology and Radiation Protection, cilt.37, sa.4, ss.334-339, 2022 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 4
  • Basım Tarihi: 2022
  • Doi Numarası: 10.2298/ntrp2204334t
  • Dergi Adı: Nuclear Technology and Radiation Protection
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Metadex, Pollution Abstracts, Directory of Open Access Journals
  • Sayfa Sayıları: ss.334-339
  • Anahtar Kelimeler: boron neutron capture therapy, MCNP program, neutron energy
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

Boron neutron capture therapy is a unique treatment method that aims to kill the tumor cellswith the help of heavy particles. Particles resulting from the inter action of the tumor regioncontaining 10B atoms with thermal or epithermal neutrons have the most important role inthis treatment method. In this study, gamma radiation reaching healthy tissues, which is theresult of 10B(n,α)7Li reaction, was investigated. A simulation suitable for boron neutron capture therapy treatment, including the human head model, was created by the Monte CarloN-Particle (MCNP) program. By using five different neutron energies, the gamma radiationsresulting from the 10B(n,α)7Li reaction in the determined regions, close to the tumor tissue,were investigated. It was observed that the healthy tissue between the tumor area and the surface is exposed to the highest gamma flux and the highest gammaradiation absorption. It wasalso observed that these values increase as neutron energy de creases. It was found that thegamma doses received by some regions outside the neutron irradiation area could be significant. It has been under stood that the change in neutron energy may cause significant changesin gamma radiation values reaching healthy tissues, especially in regions close to the surface.In boron neutron capture therapy treatments, the neutrons sent to the tumor should be selected de pending on the location of the tumor and the size of the tumor area. This study contains significant data about photon doses in healthy tissues around the brain region treatedusing different neutron energies with the boron neutron capture therapy technique.