Cinacalcet may improve oxidative DNA damage in maintenance hemodialysis patients: an observational study

ARI E., Kaya Y., Demir H., AŞICIOĞLU E., Eren Z., CELIK E., ...More

INTERNATIONAL UROLOGY AND NEPHROLOGY, vol.46, no.9, pp.1843-1849, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 9
  • Publication Date: 2014
  • Doi Number: 10.1007/s11255-014-0723-0
  • Journal Name: INTERNATIONAL UROLOGY AND NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1843-1849
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

Oxidative stress is accepted as a non-classical cardiovascular risk factor in patients on maintenance hemodialysis (HD). The aim of this study was to evaluate the impact of cinacalcet on oxidative stress biomarkers, oxidative DNA damage (8-hydroxy-2'-deoxyguanosine/deoxyguanosine), endothelial function (FMD %) and carotid artery intima-media thickness (CIMT) in HD patients.