Brachial plexus paralysis due to giant cavernous hemangioma with Kasabach-Merritt syndrome: Successful management with interferon alpha


Peker E. , KIRIMI E., Tuncer O. , CEYLAN A., Öner A. C.

PLATELETS, cilt.20, ss.603-605, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 20 Konu: 8
  • Basım Tarihi: 2009
  • Doi Numarası: 10.3109/09537100903247790
  • Dergi Adı: PLATELETS
  • Sayfa Sayıları: ss.603-605

Özet

Giant hemangiomas are rare in newborn babies and may cause some life-threatening complications such as congestive heart failure and coagulopathies including severe thrombocytopenia, microangiopathic hemolytic anemia and bleeding such as Kasabach-Merritt syndrome. We have presented here one infant case with a right lower brachial plexus paralysis due to giant hemangioma treated successfully with interferon alpha and have discussed the treatment. This is the first case of Kasabach-Merritt syndrome associated with a right lower brachial plexus paralysis treated with interferon in the literature to our knowledge. The administration of interferon-alpha might be indicated as a therapy for severe, life-threatening and giant hemangiomas such as Kasabach-Merritt syndrome, especially when there is resistance to steroid. However, more extensive data and new patients are needed to clarify this issue.