Akademik Veri Yönetim Sistemi
Van Medical Journal, cilt.32, sa.2, ss.70-79, 2025 (Scopus)
Introduction: In this study, we aimed to demonstrate the histopathological, clinical, demographic, and biochemical features of upper and lower gastrointestinal (GI) tract polyps. Additionally, we aimed to investigate the effect of polyp localization on endoscopic intervention indications, polyp size, and biochemical, histopathological, and demographic characteristics. Materials and Methods: Endoscopic procedures performed in the endoscopy unit at the Van Yüzüncü Yıl University Dursun Odabaş Medicine Center between 2016-2021 were scanned. In total, 900 patients with polyps in the upper or lower GI tract were included in this study. Endoscopic procedure reports, biochemical data (C-reactive protein (CRP), sedimentation, hemoglobin, platelet, leukocyte, red cell distribution width, and ferritin values), histopathological data, endoscopic procedure indications, and demographic data of the patients were evaluated by statistical analysis. Results: Polyps were divided into three groups according to polyp size: dimunitive polyps 61.3% (n=552); small polyps 30.3% (n=273); and large polyps 8.3% (n=75). The polyps were also divided into three groups according to their histological features: noeplastic polyps (including; adenomatous polyps (38.3%), and serrated polyps (0.3%), malignant polyps (3.7%), and non-neoplastic polyps (57.2%). The incidence of adenomatous and malignant polyps was significantly higher in the left colon, whereas that of non-neoplastic polyps were significantly higher in the upper GI tract (p=0.001). The incidence of adenomatous polyps was significantly higher in large polyps (p=0.001). We determined the CRP and leukocyte values to be significantly higher in large polyps than in other polyp sizes (p=0.01, p=0.008, respectively). The platelet count was significantly higher in malignant polyps (p=0.026). Conclusion: This study revealed significantly higher leukocyte counts in polyps with lower GI tract and left colon localization. Additionally, higher platelet counts in polyps with malignant pathology and higher CRP levels and leukocyte counts in large polyps were detected.