Analysis of Phenolic Compounds by LC-HRMS and Determination of Antioxidant and Enzyme Inhibitory Properties of Verbascum speciousum Schrad


Kızıltaş H., Bingöl Z., Gören A. C., Gülçin İ., Alwasel S.

RECORDS OF NATURAL PRODUCTS, vol.17, no.3, pp.485-500, 2023 (SCI-Expanded)

  • Publication Type: Article / Article
  • Volume: 17 Issue: 3
  • Publication Date: 2023
  • Doi Number: 10.25135/rnp.370.2210.2598
  • Journal Name: RECORDS OF NATURAL PRODUCTS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, ABI/INFORM, CAB Abstracts, EMBASE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.485-500
  • Van Yüzüncü Yıl University Affiliated: Yes

Abstract

Studies have shown an inverse correlation between age-related illnesses like coronary heart disease and cancer and fruit and vegetable intake. Given the probable health benefits of natural antioxidants from plants,

research on them has increased. Verbascum L is a large genus of Scrophulariaceae family and 323 species distributed worldwide. Since Verbascum L. species are plants that are grown in many regions of Turkiye and are

used in folk medicine, it is important to evaluate the biological activity of these species. In this study antioxidant properties of Verbascum speciosum Schrad. were investigated. The antioxidant capacities of water and ethanolbased

extracts obtained from air parts were evaluated with Fe3+ reducing, CUPRAC, FRAP, DPPH•, and ABTS•+ scavenging antioxidant methods. Extracts were also examined to determine their AChE, α-glycosidase and α-

amylase enzyme inhibitions. This investigation could be a basis for further phytochemical investigations of Verbascum speciosum Schrad.