Ionizing electromagnetic radiation interaction properties of some antihypertensive drugs


Erzen Yıldız H.

Journal of Medicine and Applied Sciences, cilt.2, sa.2, ss.29-36, 2021 (Hakemli Dergi)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 2 Sayı: 2
  • Basım Tarihi: 2021
  • Dergi Adı: Journal of Medicine and Applied Sciences
  • Sayfa Sayıları: ss.29-36
  • Van Yüzüncü Yıl Üniversitesi Adresli: Evet

Özet

In the present work, the mass attenuation coefficient (MAC), half value layer (HVL), mean free path (mfp), effective atomic number (Zeff), electron densities (Nel), exposure and absorption build-up factors (EBF and EABF) of sixantihypertensive drugs (Fisonopril, Captopril, Losartan Potassium, Irbesartan, Ramipril, Telmisartan) have calculatedusing EpiXS program as a function of gamma-ray energy. Losartan Potassium has larger MAC, Zeff and Nel values and lower HVL and mfp values than the other studied drugs. The smallest EBF and EABF values are observed for Losartan Potassium for all of the penetration depths. As a result, it can be said that losartan absorbs more photon radiation than the other drugs.

Keywords: Antihypertensive Drug, Photon interactions paramaters Mass attenuation coefficient, Exposure build-up factor