A Desensitization Protocol in Children With L-Asparaginase Hypersensitivity

AKBAYRAM S., Dogan M., AKGUN C., CAKSEN H., Oner A. F.

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, vol.32, no.5, 2010 (SCI-Expanded) identifier identifier identifier


Background: L-asparaginase is effective in the treatment of malignant diseases, but it has been associated with hypersensitivity reactions in 5% to 45% of the patients.