Synthesis of Pyrazoles via Electrophilic Cyclization of Alkynes Containing Thiophene

Cetin A.

LETTERS IN ORGANIC CHEMISTRY, vol.13, no.4, pp.310-315, 2016 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 4
  • Publication Date: 2016
  • Doi Number: 10.2174/1570178613666160128232100
  • Title of Journal : LETTERS IN ORGANIC CHEMISTRY
  • Page Numbers: pp.310-315
  • Keywords: Alkyne, electrophilic cyclization, hydrazine, hydrazone, pyrazole, ONE-POT SYNTHESIS, 1,3-DIPOLAR CYCLOADDITION, INHIBITORS, IDENTIFICATION, DERIVATIVES, EFFICIENT, REAGENT

Abstract

Background: Pyrazole is a simple aromatic ring an organic compound of the heterocyclic series that characterized five-membered ring structure which comprises located adjacent two nitrogen atoms and three carbon atoms. In recent years interest in the pyrazole chemistry excessively has increased due to many a wide range of properties. Because they have a wide range of specific properties such as biological activities, pharmaceutical i.e., Pyrazoles were also applied successfully in many fields; medicine, agricultural, industry, pharmaceutical chemistry so that pyrazole chemistry was quite an interesting area of research for the synthesis of their derivatives and investigates new methods.