Synthesis and some reactions of 4-benzoyl-5-phenyl-1-(2,4,6-trichloro phenyl)-1H-pyrazole-3-carboxylic acid
TURKISH JOURNAL OF CHEMISTRY, cilt.28, sa.2, ss.149-156, 2004 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 28 Sayı: 2
- Basım Tarihi: 2004
- Dergi Adı: TURKISH JOURNAL OF CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.149-156
- Van Yüzüncü Yıl Üniversitesi Adresli: Evet
Özet
Furandione I was reacted with 2,4,6-trichlorophenylhydrazine to give the 1H-pyrazole-3-carboxylic acid 2 together with a new pyridazinone derivative 3. Then 2 was converted into the corresponding ester 5 or amide 6 derivatives, respectively, via reactions of its acid chloride 4 with various alcohols or N-nucleophiles. Nitrile derivative 7 was obtained by dehydration of 6a in a mixture of SOCl2 and DMF. Condensation reactions of 2 with some hydrazines led to the formation of pyrazolo [3,4-d] pyridazinone 8 derivatives.